Search results for "Androgen-Insensitivity Syndrome"

showing 2 items of 2 documents

Mutations of the androgen receptor gene in patients with complete androgen insensitivity.

1997

MaleAndrogen Receptor GeneDisorders of Sex DevelopmentBiologyAndrogen-Insensitivity SyndromePolymerase Chain ReactionAndrogen receptorReceptors AndrogenMutationGeneticsCancer researchHumansIn patientFemaleComplete androgen insensitivityGenetics (clinical)Polymorphism Single-Stranded ConformationalHuman mutation
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Inhibin-α, CD99, HEA125, PLAP, and chromogranin immunoreactivity in testicular neoplasms and the androgen insensitivity syndrome

2000

We investigated 115 testicular and 3 epididymal tumors and 6 cases of the complete androgen insensitivity syndrome (AIS) for the expression of inhibin-alpha, CD99, HEA125, PLAP, and chromogranin, using monoclonal antibodies and standard immunhistochemical techniques. Ihibin-alpha was detected in the neoplastic cells in 27 of 27 primary Leydig cell tumors (LCTs), 1 of 1 metastatic LCT, 6 of 20 Sertoli cell tumors (SCTs), 4 of 5 juvenile granulosa cell tumors (GCTs), and 2 of 5 unclassified sex cord-stromal tumors (USCSTs). Except for 2 choriocarcinomas, the choriocarcinomatous component of 1 mixed germ cell tumor, and a small focus of inhibin-positive syncytiotrophoblast in 1 embryonal carci…

Maleendocrine systemmedicine.medical_specialtyPathologyendocrine system diseasesCD9912E7 AntigenBiologyPathology and Forensic MedicineEmbryonal carcinomaTesticular NeoplasmsAntigens CDAntigens NeoplasmRete testisInternal medicineBiomarkers TumorChromograninsmedicineHumansInhibinsRhabdomyosarcomaGranulosa Cell TumorEpididymisLeydig cellProteinsChromogranin AAndrogen-Insensitivity Syndromemedicine.diseaseSertoli cellNeoplasm Proteinsmedicine.anatomical_structureEndocrinologyFluorescent Antibody Technique DirectAntigens Surfacebiology.proteinGerm cell tumorsPeptidesCell Adhesion MoleculesHuman Pathology
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